Effects of arabinosylcytosine nucleosides on DNA synthesis in rats.
نویسندگان
چکیده
SUMMARY Some effects of l-@3-D-arabinofuranosylcytosine and of 1-13-D-arabinofuranosyl-5-fluorocytosine on normal prolifer ating tissues in rat are described. l-j3-D-Arabinofuranosylcyto sine at doses 1/30 the @ causes marked and transient inhibition of the incorporation oflabeled thymidine into DNA of small intestine, spleen, thymus, and regenerating liver and induces karyorrhexis in epithelial cells of duodenal crypts.
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ورودعنوان ژورنال:
- Cancer research
دوره 30 7 شماره
صفحات -
تاریخ انتشار 1970